Christopher Hoffmann, MD

Faculty

Titles:

Assistant Professor, Medicine

SciVal:

SciVal Link

Dr Hoffmann is an Assistant Professor of Medicine in the Division of Infectious Diseases with a joint appointment in the Division of Internal Medicine.  His clinical work includes inpatient and outpatient HIV care and inpatient general infectious diseases consults and general internal medicine.  His primary research interest is in reducing HIV and TB associated mortality in low and middle income countries.  He work spans several disciplines including (1) clinical epidemiology and clinical outcomes related research with HIV treatment cohorts, (2) population-level epidemiology of TB, HIV, and hepatitis B, (3) operational research around screening and testing for both TB and HIV (including in marginalized populations such as correctional facility inmates), (4) implementation science to understand and improve scale-up of proven interventions through the use of pragmatic clinical trials, (5) health economics to contextualize operational research and implementation science findings. The majority of his work is in southern Africa.  Current projects include assessments of interventions to increase entry-into-care following HIV diagnosis, retention in HIV care, managing HIV and TB care transitions, improved TB intensified case finding, TB and HIV management in correctional facilities, and adapting quality improvement approaches for primary health clinics in South Africa.  He is also involved in several projects aimed at assessing current HIV care with the goal of contributing to improving outcomes while using existing antiretroviral agents and delivery infrastructure. I also teach a module on global health delivery at the School of Medicine.

Categories

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Projects

APT: Assessing PA-824 for Tuberculosis

A Phase 2 clinical trial of PA-824, an investigational nitroimidazole, as part of multidrug therapy for pulmonary TB; in...

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Population-level impact of isoniazid...

We are collaborating with a team that conducted a randomized trial of IPT in Khayelitsha, South Africa, to extend their findings...

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A randomized trial of preventive therapy for...

We are evaluating the efficacy and cost-effectiveness of levofloxacin preventive therapy for adult contacts of MDR TB patients...

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Statins as adjunctive host-directed therapy...

This study will investigate the role of statins in combination with the first-line regimen for TB in the mouse model. In...

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Modeling the impact of spatially targeted TB...

We have developed transmission models to understand the impact of TB vaccination strategies that target hotspots of...

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