Jason Farley, PhD, MPH, CRNP, FAAN

Faculty

Titles:

Associate Professor, School of Nursing

SciVal:

SciVal Link

Dr. Jason Farley, Director of the Johns Hopkins National AIDS Education and Training Center, is an Associate Professor of Nursing and an Adult Nurse Practitioner in the Division of Infectious Diseases and President-Elect of the Association of Nurses in AIDS Care (ANAC).  I have 16 years of nursing experience with 11 years of clinical experience as an HIV/AIDS adult primary care nurse practitioner in the Moore Clinic of the Johns Hopkins AIDS Service. I am a Fellow in the American Academy of Nursing and hold an adjunct Associate Professor appointment at the University of KwaZulu Natal in the School of Nursing and Public Health, South Africa and the University of Technology Sydney, Australia.  My work is primarily in South Africa and includes epidemiologic, interventional and implementation science research as well as capacity development initiatives with a specific focus on the intersection of HIV/AIDS and associated co-morbidities, particularly in the realm of co-infections harboring antimicrobial resistance.  My primary interests are: 

(1) Patient-Centered Outcomes Research. Through an NIAID/NIH funded R01, I am conducting a cluster randomized trial of nurse case management as an intervention to improve MDR-TB treatment outcomes among HIV co-infected patients.  My team, in collaboration with the Medical Research Council, also published a large cohort study of MDR-TB outcomes by HIV status prior to ART access from South Africa called the DOTS Plus Study. 

(2) Expanded Access to Care Models and Implementation Science. I am currently the PI on a Centers for Disease Control and Prevention supported MDR-TB project and the primary MDR-TB sub-recipient of a Global Fund for AIDS, TB and Malaria grant in collaboration with the South African National Department of Health Drug Resistant TB Directorate and JHPIEGO-South Africa.  Each of these efforts encompasses programmatic and implementation science initiatives that include the whole of South Africa with a team of over 50 individuals.  Through these programs we are expanding access to community-based care models where nurse are the primary treating clinician.  In this role, I serve on a strategic planning committee (think tank) for the South Africa National Department of Health Drug Resistant TB Directorate. 

(3) TB Infection Prevention and Control (IPC).  My work in TB-IPC includes the assessment and evaluation of MDR-TB hospitals throughout South Africa with regard to the human factors of TB-IPC.  My team has focused on the protection of both healthcare workers and patients in these settings.  I also strongly believe that these protections should be implemented across the care continuum and in both clinical and research settings. 

(4) Capacity Development and Mentoring.  Teaching and mentoring of pre-service and in-service healthcare workers is exceptionally important.  To do this on a greater scale than I could ever do in person, I co-teach with Dr. Chaisson a Coursera open course of TB Clinical Management and Research.  To date, participants from 126 countries have participated in this course.   Outside of this course, my team offers a one week didactic inter-professional training to nurses, physicians and other healthcare workers in MDR-TB Management in South Africa.  This includes capacitating primary healthcare nurses (nurse practitioner) to diagnose, treat and manage MDR-TB patients.  Finally, I see the mentorship of doctoral students and post-docs as a key priority to grow the next generation of scientist in TB. 

  1. Provision of guideline-based care for drug-resistant tuberculosis in South Africa: Level of concordance between prescribing practices and guidelines; PLoS ONE
  2. Effectiveness of macronutrient supplementation on nutritional status and HIV/AIDS progression in sub-Saharan Africa: A systematic review and meta-analysis; Clinical Nutrition ESPEN
  3. A systematic review of smoking cessation interventions among patients with tuberculosis ; Public Health Action
  4. Community health worker interventions to promote psychosocial outcomes among people living with HIV ; PLoS ONE
  5. Barriers to tuberculosis and human immunodeficiency virus treatment guidelines adherence among nurse initiating and managing anti-retroviral therapy in KwaZulu-Natal and North West provinces; Curationis
  6. Impact of intimate partner violence on clinic attendance, viral suppression and CD4 cell count of women living with HIV in an urban clinic setting; AIDS Care
  7. Time to drug-resistant tuberculosis treatment in a prospective South African cohort ; Global Pediatric Health
  8. Identifying models of HIV care and treatment service delivery in Tanzania, Uganda, and Zambia using cluster analysis and Delphi survey; BMC Health Services Research
  9. TB risk perceptions among medical residents at a tertiary care center in India ; Tuberculosis Research and Treatment
  10. Evaluation of a nurse practitioner-physician task-sharing model for multidrug-resistant tuberculosis in South Africa; PLoS ONE
  11. Behavioral and other patient characteristics associated with HIV viral suppression in an outpatient clinic; PLoS ONE
  12. Highlighting the need for more infection control practitioners in low and middle income countries ; Public Health Action
  13. Engaging health-care workers to reduce tuberculosis transmission ; The Lancet Infectious Diseases
  14. Occupational risk factors for TB among health care workers in KwaZulu-Natal, South Africa ; Clinical Infectious Diseases
  15. Infection control for drug-resistant tuberculosis: early diagnosis and treatment is the key ; Clinical Infectious Diseases
  16. Discordance between patient and provider report of multidrug-resistant tuberculosis adverse drug reactions; International Journal of Tuberculosis and Lung Disease
  17. Perspectives of nursing faculty in Africa on global health competencies ; Nursing Outlook
  18. A randomized trial of HPV self-sampling as an intervention to promote cervical cancer screening in women with HIV; Journal of Lower Genital Tract Disease
  19. Development and evaluation of a nurse case management model to address HIV and MDR-TB in South Africa; PLoS ONE
  20. Knowledge, attitudes and practice of OB-GYN nurses and auxiliary staff in the care of pregnant women living in HIV; Journal of the Association of Nurses in AIDS Care
  21. Tuberculosis among healthcare workers in KwaZulu-Natal, South Africa: a retrospective cohort analysis; BMC: Public Health
  22. Optimizing the protection of research participants and personnel in HIV-related research where TB is prevalent: practical solutions for improving infection control; Journal of Acquired Immune Deficiency Syndromes
  23. Smoking cessation interventions in persons living with HIV and AIDS: A systematic review ; Journal of the Association of Nurses in AIDS Care
  24. Healthcare workers’ fears associated with working in multidrug-and or extensively-resistant TB wards in South Africa; International Journal of Tuberculosis and Lung Disease
  25. Occupational health policies and practices related to TB in health care workers in KwaZulu-Natal, South Africa; Public Health Action
  26. Serious treatment related adverse drug related reactions amongst anti-retroviral naïve MDR-TB patients; PLoS ONE
  27. An infection control audit of 10 primary healthcare facilities in western cape, South Africa; International Journal of Infection Control
  28. Global health competencies for nurses in the Americas ; Journal of Professional Nursing
  29. A national infection control evaluation of drug resistant tuberculosis hospitals in South Africa ; International Journal of Tuberculosis and Lung Disease
  30. Department of health and human services releases new immersive simulation experience to improve improve infection control knowledge and practices among healthcare workers and students; American Journal of Infection Control
  31. Outcomes of multi-drug resistant tuberculosis (MDR-TB) among a cohort of South African patients with high HIV prevalence; PLoS ONE

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Projects

mHealth for improved TB contact investigation...

This multicenter randomized study is evaluating the implementation, effectiveness, cost-effectiveness, and population-level...

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Modeling the impact of spatially targeted TB...

 We have developed transmission models to understand the impact of TB vaccination strategies that target hotspots of...

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A Nurse Case Management Intervention to...

Dr. Farley is responsible for the overall project from design, implementation, data collection, and preparation of...

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Immunotherapy Targeting MTB Persisters in the...

The goal of this research program is to determine whether enhanced immunity to critical components of the Mtb stringent response...

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A randomized trial of preventive therapy for...

We are evaluating the efficacy and cost-effectiveness of levofloxacin preventive therapy for pediatric contacts of MDR TB...

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