Larry Moulton, PhD

Faculty

Titles:

Professor, International Health, Biostatistics

SciVal:

SciVal Link

I am involved in several group-randomized trials; those involving vaccines are especially interesting, as they afford the opportunity to measure indirect effects of immunization. I am working on methods for the design, especially the randomization, of such trials, as well as methods of analysis of the resulting correlated data.

My involvement with HIV and TB research began in the early 1990s when I started working for the Johns Hopkins University as a statistician on HIV studies and TB trials in Haiti.  I have been the principal statistician on a number of HIV and TB related studies (including the 14,000+ mother-infant pairs in the ZVITAMBO project in Zimbabwe, the male circumcision trial in Uganda, the trial of rifapentine and extended INH prophylaxis for HIV-related TB in Soweto, and the THRio study in Brazil).

My expertise is in correlated data analysis, study design, and statistical epidemiology.  In particular, I am working on the design and analysis of cluster randomized trials, especially their randomization.  I direct the Ph.D. program in Global Disease Epidemiology and Control and the Peace Corps/Masters International Program, I am Co-Director of the Institute for Vaccine Safety, and Director of the Biostatistics and Epidemiology Methodology Core of the JHU Center For AIDS Research.

Categories

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Projects

Understanding and Improving the Effectiveness...

The goal of this project is to construct a mathematical model of the laboratory network for diagnosis of infectious diseases in...

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Comparative Effectiveness/Implementation of...

This cluster-randomized trial in 56 rural primary care clinics compares the effectiveness and implementation of three strategies...

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Evaluation of a novel serum biosignature for...

This study will use multiple high-throughput modalities, including LC-MS/MS and RNA-seq, to detect a panel of host metabolites...

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Scale-up and implementation of TB diagnostics...

We are evaluating the implementation, cost-effectiveness, and potential epidemiological impact of scaling up Xpert across 19...

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