Larry Moulton, PhD

Faculty

Titles:

Professor, International Health, Biostatistics

SciVal:

SciVal Link

I am involved in several group-randomized trials; those involving vaccines are especially interesting, as they afford the opportunity to measure indirect effects of immunization. I am working on methods for the design, especially the randomization, of such trials, as well as methods of analysis of the resulting correlated data.

My involvement with HIV and TB research began in the early 1990s when I started working for the Johns Hopkins University as a statistician on HIV studies and TB trials in Haiti.  I have been the principal statistician on a number of HIV and TB related studies (including the 14,000+ mother-infant pairs in the ZVITAMBO project in Zimbabwe, the male circumcision trial in Uganda, the trial of rifapentine and extended INH prophylaxis for HIV-related TB in Soweto, and the THRio study in Brazil).

My expertise is in correlated data analysis, study design, and statistical epidemiology.  In particular, I am working on the design and analysis of cluster randomized trials, especially their randomization.  I direct the Ph.D. program in Global Disease Epidemiology and Control and the Peace Corps/Masters International Program, I am Co-Director of the Institute for Vaccine Safety, and Director of the Biostatistics and Epidemiology Methodology Core of the JHU Center For AIDS Research.

Categories

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Projects

Modeling to improve TB decision-making in the...

We are part of a large consortium that is constructing epidemic and economic models of TB and HIV in collaboration with the U.S....

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Assessing the social value of novel regimens...

We are collaborating with investigators from the Berman Bioethics Institute to develop novel techniques for economic evaluation...

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TBM-KIDS (Malawi)

A phase 2 clinical trial of optimized treatment for pediatric tuberculous meningitis in India and Malawi

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Comparative Effectiveness/Implementation of...

This cluster-randomized trial in 56 rural primary care clinics compares the effectiveness and implementation of three strategies...

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Decentralized testing for tuberculosis with...

This is a highly pragmatic cluster randomized trial to compare the impact, implementation, and cost-effectiveness of on-site...

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