Paul Converse, PhD

Titles:

Research Analyst, Hopkins Medicine

SciVal:

SciVal Link

My research interests concern the pathogens, Mycobacterium tuberculosis and M. ulcerans, in humans and experimental animal hosts. Studies in tuberculosis, principally in the mouse model, concern the response to chemotherapeutic agents, including novel compounds and novel combinations of drugs, and their modulation due to innate host factors and those involving the immune system after immunotherapeutic vaccination. Studies on M. ulcerans, the causative agent of Buruli ulcer, have focused on the differential response to vaccination in different mouse strains and the evaluation of novel chemotherapy regimens in comparison with the WHO standard of rifampin and streptomycin. We are also involved in studies to develop appropriate assays to detect mycolactone, the toxin that is the principal virulence factor of M. ulcerans.

Categories

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Projects

Impact of diabetes on TB treatment outcomes...

This is a study to prospectively enroll and follow TB patients co-infected with diabetes and TB patients without diabetes...

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TBM-KIDS (Malawi)

A phase 2 clinical trial of optimized treatment for pediatric tuberculous meningitis in India and Malawi

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ICOHRTA Training Program (Fogarty)

International Clinical, Operational, and Health Services Research Award (ICOHRTA) training program. A training program that...

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Understanding the role of repeat testing and...

We have developed a Markov model of serial IGRA testing to help improve testing algorithms with TST vs. IGRA in low-risk...

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Quantitative assessment of the tipping point...

Quantitative methods will be used to study Mtb dynamics to determine the tipping point for macrophage infection, which depends...

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