Paul Converse, PhD

Titles:

Research Analyst, Hopkins Medicine

SciVal:

SciVal Link

My research interests concern the pathogens, Mycobacterium tuberculosis and M. ulcerans, in humans and experimental animal hosts. Studies in tuberculosis, principally in the mouse model, concern the response to chemotherapeutic agents, including novel compounds and novel combinations of drugs, and their modulation due to innate host factors and those involving the immune system after immunotherapeutic vaccination. Studies on M. ulcerans, the causative agent of Buruli ulcer, have focused on the differential response to vaccination in different mouse strains and the evaluation of novel chemotherapy regimens in comparison with the WHO standard of rifampin and streptomycin. We are also involved in studies to develop appropriate assays to detect mycolactone, the toxin that is the principal virulence factor of M. ulcerans.

Categories

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July 2018

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Projects

Understanding the costs and...

We have conducted an empirical costing analysis of facility-based versus community-based treatment for TB in Bangladesh and are...

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A randomized trial of preventive therapy for...

We are evaluating the efficacy and cost-effectiveness of levofloxacin preventive therapy for adult contacts of MDR TB patients...

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Modeling the impact of spatially targeted TB...

 We have developed transmission models to understand the impact of TB vaccination strategies that target hotspots of...

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Understanding the impact of combined TB and...

We are developing models to understand the overlap of TB and HIV in three epidemiologically distinct settings (Canada, India,...

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Impact of diabetes on TB treatment outcomes...

This is a study to prospectively enroll and follow TB patients co-infected with diabetes and TB patients without diabetes...

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