Paul Converse, PhD

Titles:

Research Analyst, Hopkins Medicine

SciVal:

SciVal Link

My research interests concern the pathogens, Mycobacterium tuberculosis and M. ulcerans, in humans and experimental animal hosts. Studies in tuberculosis, principally in the mouse model, concern the response to chemotherapeutic agents, including novel compounds and novel combinations of drugs, and their modulation due to innate host factors and those involving the immune system after immunotherapeutic vaccination. Studies on M. ulcerans, the causative agent of Buruli ulcer, have focused on the differential response to vaccination in different mouse strains and the evaluation of novel chemotherapy regimens in comparison with the WHO standard of rifampin and streptomycin. We are also involved in studies to develop appropriate assays to detect mycolactone, the toxin that is the principal virulence factor of M. ulcerans.

Categories

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March 2017

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Projects

TB Modeling and Analysis Consortium

The TB MAC brings TB modelers together from a wide range of institutions to answer questions of global policy relevance.  I...

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Understanding the role of repeat testing and...

We have developed a Markov model of serial IGRA testing to help improve testing algorithms with TST vs. IGRA in low-risk...

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Comparative implementation and...

We are conducting a randomized comparative implementation trial across 56 sites in rural South Africa to evaluate three...

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Population-level impact of isoniazid...

We are collaborating with a team that conducted a randomized trial of IPT in Khayelitsha, South Africa, to extend their findings...

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