A Blueprint for Success: Understanding the epidemic of TB in New York City

Location

New York, NY, US

Dates

07/25/2015 - 06/25/2015

PI

David Dowdy, MD, PhD, ScM

We are using a combination of statistical analysis and transmission modeling, in collaboration with the NYC Dept of Health & Mental Hygiene, to better understand the dynamics of TB transmission in New York City and to explain how the tide was turned against the epidemic of TB and MDR-TB in the early 1990s.

Projects

The role of cell wall lipids in pathogenesis...

This study will use a combination of transcriptional, lipidomic, genetic, and imaging techniques to investigate whether...

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mHealth for improved TB contact investigation...

This multicenter randomized study is evaluating the implementation, effectiveness, cost-effectiveness, and population-level...

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Quantitative assessment of the tipping point...

Quantitative methods will be used to study Mtb dynamics to determine the tipping point for macrophage infection, which depends...

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A randomized trial of preventive therapy for...

We are evaluating the efficacy and cost-effectiveness of levofloxacin preventive therapy for adult contacts of MDR TB patients...

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