A randomized trial of preventive therapy for adult MDR TB contacts

Location

Vietnam, Vietnam

Dates

08/01/2014 - 07/01/2019

PI

David Dowdy, MD, PhD, ScM

We are evaluating the efficacy and cost-effectiveness of levofloxacin preventive therapy for adult contacts of MDR TB patients in Vietnam.  I am the primary economic lead.

People

Kelly Dooley, MD, PhD
Faculty
Amita Gupta, MD, MHS
Faculty
Petros Karakousis, MD
Faculty
Sanjay Jain, MD
Faculty
Neil Martinson, MD, MPH
Faculty

Projects

Evaluating an automated system for...

We are evaluating the accuracy and cost-effectiveness of TBDx, an automated digital microscopy system, as a screening test to...

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Statins as adjunctive host-directed therapy...

This study will investigate the role of statins in combination with the first-line regimen for TB in the mouse model. In...

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A novel “shock and kill” strategy...

The objective of this study is to determine if pharmacological inhibition of the Mtb stringent response leads to accelerated...

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TBM-KIDS (India)

A phase 2 clinical trial of optimized treatment for pediatric tuberculous meningitis in India and Malawi

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Statins as Adjunctive, Host-Directed Therapy...

The goal of this study is to investigate the potential utility of pravastatin as an adjunctive, host-directed therapy for...

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