ACTG trial A5343

Location

South Africa

Dates

01/18/2038 - 01/18/2038

PI

Kelly Dooley, MD, PhD

Phase 2 safety study of bedaquiline and delamanid for the treatment of MDR-TB in South Africa

Projects

TB Modeling and Analysis Consortium

The TB MAC brings TB modelers together from a wide range of institutions to answer questions of global policy relevance.  I...

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A Blueprint for Success: Understanding the...

We are using a combination of statistical analysis and transmission modeling, in collaboration with the NYC Dept of Health &...

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Quantitative assessment of the tipping point...

Quantitative methods will be used to study Mtb dynamics to determine the tipping point for macrophage infection, which depends...

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The role of cell wall lipids in pathogenesis...

This study will use a combination of transcriptional, lipidomic, genetic, and imaging techniques to investigate whether...

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Evaluating an automated system for...

We are evaluating the accuracy and cost-effectiveness of TBDx, an automated digital microscopy system, as a screening test to...

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