APT: Assessing PA-824 for Tuberculosis

Location

Cape Town, South Africa

Dates

01/18/2038 - 01/18/2038

PI

Kelly Dooley, MD, PhD

A Phase 2 clinical trial of PA-824, an investigational nitroimidazole, as part of multidrug therapy for pulmonary TB; in partnership with UCT Lung Institute

Projects

Modeling the impact of spatially targeted TB...

 We have developed transmission models to understand the impact of TB vaccination strategies that target hotspots of...

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Statins as adjunctive host-directed therapy...

This study will investigate the role of statins in combination with the first-line regimen for TB in the mouse model. In...

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ICOHRTA Training Program (Fogarty)

International Clinical, Operational, and Health Services Research Award (ICOHRTA) training program. A training program that...

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MDR TB treatment as prevention: modeling the...

We are using transmission modeling to evaluate the potential impact of expanding DST and access to MDR TB treatment in Vietnam,...

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