Comparative implementation and cost-effectiveness of active TB case finding in rural South Africa


Vhembe, South Africa, South Africa


01/25/2015 - 12/01/2019


David Dowdy, MD, PhD, ScM

We are conducting a randomized comparative implementation trial across 56 sites in rural South Africa to evaluate three strategies for active case finding: facility-based screening, household contact tracing, and incentive-based contact tracing.


ACTG trial A5343

Phase 2 safety study of bedaquiline and delamanid for the treatment of MDR-TB in South Africa

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Understanding and Improving the Effectiveness...

The goal of this project is to construct a mathematical model of the laboratory network for diagnosis of infectious diseases in...

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APT: Assessing PA-824 for Tuberculosis

A Phase 2 clinical trial of PA-824, an investigational nitroimidazole, as part of multidrug therapy for pulmonary TB; in...

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Population-level impact of isoniazid...

We are collaborating with a team that conducted a randomized trial of IPT in Khayelitsha, South Africa, to extend their findings...

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ICOHRTA Training Program (Fogarty)

International Clinical, Operational, and Health Services Research Award (ICOHRTA) training program. A training program that...

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