Comparative implementation and cost-effectiveness of active TB case finding in rural South Africa

Location

Vhembe, South Africa, South Africa

Dates

01/25/2015 - 12/01/2019

PI

David Dowdy, MD, PhD, ScM

We are conducting a randomized comparative implementation trial across 56 sites in rural South Africa to evaluate three strategies for active case finding: facility-based screening, household contact tracing, and incentive-based contact tracing.

Projects

Quantiferon gold test for detecting TB...

This is a cluster randomized trial comparing the time to known latent TB status among HIV infected patients receiving QGIT...

Read More

Modeling to improve TB decision-making in the...

We are part of a large consortium that is constructing epidemic and economic models of TB and HIV in collaboration with the U.S....

Read More

mHealth for improved TB contact investigation...

This multicenter randomized study is evaluating the implementation, effectiveness, cost-effectiveness, and population-level...

Read More

The role of cell wall lipids in pathogenesis...

This study will use a combination of transcriptional, lipidomic, genetic, and imaging techniques to investigate whether...

Read More

TBM-KIDS (Malawi)

A phase 2 clinical trial of optimized treatment for pediatric tuberculous meningitis in India and Malawi

Read More