Comparative implementation and cost-effectiveness of active TB case finding in rural South Africa

Location

Vhembe, South Africa, South Africa

Dates

01/25/2015 - 12/01/2019

PI

David Dowdy, MD, PhD, ScM

We are conducting a randomized comparative implementation trial across 56 sites in rural South Africa to evaluate three strategies for active case finding: facility-based screening, household contact tracing, and incentive-based contact tracing.

Projects

Understanding the costs and...

We have conducted an empirical costing analysis of facility-based versus community-based treatment for TB in Bangladesh and are...

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Quantitative assessment of the tipping point...

Quantitative methods will be used to study Mtb dynamics to determine the tipping point for macrophage infection, which depends...

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Understanding the impact of combined TB and...

We are developing models to understand the overlap of TB and HIV in three epidemiologically distinct settings (Canada, India,...

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Modeling the impact of novel TB drug regimens...

We are constructing mathematical models of TB epidemics in Southeast Asia, India, and Vietnam to explore the potential...

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TBM-KIDS (Malawi)

A phase 2 clinical trial of optimized treatment for pediatric tuberculous meningitis in India and Malawi

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