Comparative implementation and cost-effectiveness of active TB case finding in rural South Africa

Location

Vhembe, South Africa, South Africa

Dates

01/25/2015 - 12/01/2019

PI

David Dowdy, MD, PhD, ScM

We are conducting a randomized comparative implementation trial across 56 sites in rural South Africa to evaluate three strategies for active case finding: facility-based screening, household contact tracing, and incentive-based contact tracing.

Projects

TBM-KIDS (India)

A phase 2 clinical trial of optimized treatment for pediatric tuberculous meningitis in India and Malawi

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Population-level impact of isoniazid...

We are collaborating with a team that conducted a randomized trial of IPT in Khayelitsha, South Africa, to extend their findings...

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A randomized trial of preventive therapy for...

We are evaluating the efficacy and cost-effectiveness of levofloxacin preventive therapy for pediatric contacts of MDR TB...

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mHealth for improved TB contact investigation...

This multicenter randomized study is evaluating the implementation, effectiveness, cost-effectiveness, and population-level...

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A randomized trial of preventive therapy for...

We are evaluating the efficacy and cost-effectiveness of levofloxacin preventive therapy for adult contacts of MDR TB patients...

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