Evaluating an automated system for fluorescence microscopy with digital signature mapping

Location

South Africa, South Africa

Dates

08/01/2013 - 12/01/2015

PI

David Dowdy, MD, PhD, ScM

We are evaluating the accuracy and cost-effectiveness of TBDx, an automated digital microscopy system, as a screening test to reduce the need for Xpert testing in high-volume settings.

Projects

Understanding the role of repeat testing and...

We have developed a Markov model of serial IGRA testing to help improve testing algorithms with TST vs. IGRA in low-risk...

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Impact of diabetes on TB treatment outcomes...

This is a study to prospectively enroll and follow TB patients co-infected with diabetes and TB patients without diabetes...

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The role of cell wall lipids in pathogenesis...

This study will use a combination of transcriptional, lipidomic, genetic, and imaging techniques to investigate whether...

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Statins as adjunctive host-directed therapy...

This study will investigate the role of statins in combination with the first-line regimen for TB in the mouse model. In...

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