Evaluation of a novel serum biosignature for detecting TB in HIV-infected individuals

Location

Baltimore, Maryland

Dates

06/30/2017 - 06/29/2018

PI

Petros Karakousis, MD

This study will use multiple high-throughput modalities, including LC-MS/MS and RNA-seq, to detect a panel of host metabolites and miRNAs associated with active TB in HIV-infected individuals. Clinical samples are available through the Regional Prospective Observational Research in Tuberculosis (RePORT) International Consortium.

Projects

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A Nurse Case Management Intervention to...

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Quantitative assessment of the tipping point...

Quantitative methods will be used to study Mtb dynamics to determine the tipping point for macrophage infection, which depends...

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TBM-KIDS (India)

A phase 2 clinical trial of optimized treatment for pediatric tuberculous meningitis in India and Malawi

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