MDR TB treatment as prevention: modeling the impact of improved MDR treatment in Vietnam

Location

Vietnam, Vietnam

Dates

09/01/2014 - 08/01/2015

PI

David Dowdy, MD, PhD, ScM

We are using transmission modeling to evaluate the potential impact of expanding DST and access to MDR TB treatment in Vietnam, demonstrating that better treatment of MDR TB can have tremendous impact in preventing future transmission.

Projects

A novel “shock and kill” strategy...

The objective of this study is to determine if pharmacological inhibition of the Mtb stringent response leads to accelerated...

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ACTG trial A5343

Phase 2 safety study of bedaquiline and delamanid for the treatment of MDR-TB in South Africa

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Quantitative assessment of the tipping point...

Quantitative methods will be used to study Mtb dynamics to determine the tipping point for macrophage infection, which depends...

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Human-centered Design and Communities of...

The goal of this project is to use local communities of practice and the emerging technique of human-centered design to improve...

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TB Modeling and Analysis Consortium

The TB MAC brings TB modelers together from a wide range of institutions to answer questions of global policy relevance.  I...

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