MDR TB treatment as prevention: modeling the impact of improved MDR treatment in Vietnam

Location

Vietnam, Vietnam

Dates

09/01/2014 - 08/01/2015

PI

David Dowdy, MD, PhD, ScM

We are using transmission modeling to evaluate the potential impact of expanding DST and access to MDR TB treatment in Vietnam, demonstrating that better treatment of MDR TB can have tremendous impact in preventing future transmission.

Projects

APT: Assessing PA-824 for Tuberculosis

A Phase 2 clinical trial of PA-824, an investigational nitroimidazole, as part of multidrug therapy for pulmonary TB; in...

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Impact of diabetes on TB treatment outcomes...

This is a study to prospectively enroll and follow TB patients co-infected with diabetes and TB patients without diabetes...

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Quantitative assessment of the tipping point...

Quantitative methods will be used to study Mtb dynamics to determine the tipping point for macrophage infection, which depends...

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Comparative implementation and...

We are conducting a randomized comparative implementation trial across 56 sites in rural South Africa to evaluate three...

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