Modeling the impact of novel TB drug regimens and drug susceptibility tests

Location

Baltimore, Maryland, US

Dates

04/01/2013 - 06/01/2015

PI

David Dowdy, MD, PhD, ScM

We are constructing mathematical models of TB epidemics in Southeast Asia, India, and Vietnam to explore the potential population-level impact of drug susceptibility testing and novel TB drug regimens including PaMZ on the epidemic of MDR TB.

Projects

Modeling the impact of spatially targeted TB...

We have developed transmission models to understand the impact of TB vaccination strategies that target hotspots of...

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Population-level impact of isoniazid...

We are collaborating with a team that conducted a randomized trial of IPT in Khayelitsha, South Africa, to extend their findings...

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A Nurse Case Management Intervention to...

Dr. Farley is responsible for the overall project from design, implementation, data collection, and preparation of...

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APT: Assessing PA-824 for Tuberculosis

A Phase 2 clinical trial of PA-824, an investigational nitroimidazole, as part of multidrug therapy for pulmonary TB; in...

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Understanding the costs and...

We have conducted an empirical costing analysis of facility-based versus community-based treatment for TB in Bangladesh and are...

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