Modeling the impact of spatially targeted TB vaccines

Location

South Africa, South Africa

Dates

01/01/2014 - 04/01/2015

PI

David Dowdy, MD, PhD, ScM

 We have developed transmission models to understand the impact of TB vaccination strategies that target hotspots of transmission, relative to general untargeted vaccination strategies, as a function of geographical heterogeneity and population mixing.

Projects

mHealth for improved TB contact investigation...

This multicenter randomized study is evaluating the implementation, effectiveness, cost-effectiveness, and population-level...

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A Blueprint for Success: Understanding the...

We are using a combination of statistical analysis and transmission modeling, in collaboration with the NYC Dept of Health &...

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APT: Assessing PA-824 for Tuberculosis

A Phase 2 clinical trial of PA-824, an investigational nitroimidazole, as part of multidrug therapy for pulmonary TB; in...

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Comparative Effectiveness/Implementation of...

This cluster-randomized trial in 56 rural primary care clinics compares the effectiveness and implementation of three strategies...

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A Nurse Case Management Intervention to...

Dr. Farley is responsible for the overall project from design, implementation, data collection, and preparation of...

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