Modeling the impact of spatially targeted TB vaccines

Location

Gujarat, India, India

Dates

01/01/2014 - 04/01/2015

PI

David Dowdy, MD, PhD, ScM

We have developed transmission models to understand the impact of TB vaccination strategies that target hotspots of transmission, relative to general untargeted vaccination strategies, as a function of geographical heterogeneity and population mixing.

Projects

The role of cell wall lipids in pathogenesis...

This study will use a combination of transcriptional, lipidomic, genetic, and imaging techniques to investigate whether...

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Scale-up and implementation of TB diagnostics...

We are evaluating the implementation, cost-effectiveness, and potential epidemiological impact of scaling up Xpert across 19...

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A randomized trial of preventive therapy for...

We are evaluating the efficacy and cost-effectiveness of levofloxacin preventive therapy for adult contacts of MDR TB patients...

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