Options for Patient-Centered Delivery of Short-Course Preventive Therapy for Tuberculosis: The 3HP

This individually randomized trial is evaluating the relative effectiveness of self-administered therapy, directly observed therapy, and informed patient choice for delivery of 3HP, a three-month regimen for treatment of latent TB infection, among people living with HIV in Kampala, Uganda

Projects

Modeling to improve TB decision-making in the...

We are part of a large consortium that is constructing epidemic and economic models of TB and HIV in collaboration with the U.S....

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Understanding the role of repeat testing and...

We have developed a Markov model of serial IGRA testing to help improve testing algorithms with TST vs. IGRA in low-risk...

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Quantitative assessment of the tipping point...

Quantitative methods will be used to study Mtb dynamics to determine the tipping point for macrophage infection, which depends...

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The role of cell wall lipids in pathogenesis...

This study will use a combination of transcriptional, lipidomic, genetic, and imaging techniques to investigate whether...

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