Population-level impact of isoniazid preventive therapy in South Africa

Location

Khayelitsha, South Africa, South Africa

Dates

08/01/2012 - 07/01/2015

PI

David Dowdy, MD, PhD, ScM

We are collaborating with a team that conducted a randomized trial of IPT in Khayelitsha, South Africa, to extend their findings and understand the potential population-level impact of IPT in this unique epidemiological setting.

Projects

Evaluating an automated system for...

We are evaluating the accuracy and cost-effectiveness of TBDx, an automated digital microscopy system, as a screening test to...

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The role of cell wall lipids in pathogenesis...

This study will use a combination of transcriptional, lipidomic, genetic, and imaging techniques to investigate whether...

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Immunotherapy Targeting MTB Persisters in the...

The goal of this research program is to determine whether enhanced immunity to critical components of the Mtb stringent response...

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Comparative Effectiveness/Implementation of...

This cluster-randomized trial in 56 rural primary care clinics compares the effectiveness and implementation of three strategies...

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