Population-level impact of isoniazid preventive therapy in South Africa

Location

Khayelitsha, South Africa, South Africa

Dates

08/01/2012 - 07/01/2015

PI

David Dowdy, MD, PhD, ScM

We are collaborating with a team that conducted a randomized trial of IPT in Khayelitsha, South Africa, to extend their findings and understand the potential population-level impact of IPT in this unique epidemiological setting.

Projects

APT: Assessing PA-824 for Tuberculosis

A Phase 2 clinical trial of PA-824, an investigational nitroimidazole, as part of multidrug therapy for pulmonary TB; in...

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Impact of diabetes on TB treatment outcomes...

This is a study to prospectively enroll and follow TB patients co-infected with diabetes and TB patients without diabetes...

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Quantitative assessment of the tipping point...

Quantitative methods will be used to study Mtb dynamics to determine the tipping point for macrophage infection, which depends...

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A Blueprint for Success: Understanding the...

We are using a combination of statistical analysis and transmission modeling, in collaboration with the NYC Dept of Health &...

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