Population-level impact of isoniazid preventive therapy in South Africa

Location

Khayelitsha, South Africa, South Africa

Dates

08/01/2012 - 07/01/2015

PI

David Dowdy, MD, PhD, ScM

We are collaborating with a team that conducted a randomized trial of IPT in Khayelitsha, South Africa, to extend their findings and understand the potential population-level impact of IPT in this unique epidemiological setting.

Projects

The role of cell wall lipids in pathogenesis...

This study will use a combination of transcriptional, lipidomic, genetic, and imaging techniques to investigate whether...

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Population-level impact of isoniazid...

We are collaborating with a team that conducted a randomized trial of IPT in Khayelitsha, South Africa, to extend their findings...

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Quantitative assessment of the tipping point...

Quantitative methods will be used to study Mtb dynamics to determine the tipping point for macrophage infection, which depends...

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Understanding the impact of combined TB and...

We are developing models to understand the overlap of TB and HIV in three epidemiologically distinct settings (Canada, India,...

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