Quantitative assessment of the tipping point in Mycobacterium tuberculosis transmission and

Location

Baltimore, Maryland, US

Dates

12/01/2014 - 11/30/2017

PI

Petros Karakousis, MD

Quantitative methods will be used to study Mtb dynamics to determine the tipping point for macrophage infection, which depends on the number and state of internalized bacteria and leads to either control of infection or uncontrolled Mtb replication.

Projects

Understanding the impact of combined TB and...

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A randomized trial of preventive therapy for...

We are evaluating the efficacy and cost-effectiveness of levofloxacin preventive therapy for pediatric contacts of MDR TB...

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