Quantitative assessment of the tipping point in Mycobacterium tuberculosis transmission and

Location

Baltimore, Maryland, US

Dates

12/01/2014 - 11/30/2017

PI

Petros Karakousis, MD

Quantitative methods will be used to study Mtb dynamics to determine the tipping point for macrophage infection, which depends on the number and state of internalized bacteria and leads to either control of infection or uncontrolled Mtb replication.

Projects

Quantitative assessment of the tipping point...

Quantitative methods will be used to study Mtb dynamics to determine the tipping point for macrophage infection, which depends...

Read More

TBM-KIDS (Malawi)

A phase 2 clinical trial of optimized treatment for pediatric tuberculous meningitis in India and Malawi

Read More

Quantiferon gold test for detecting TB...

This is a cluster randomized trial comparing the time to known latent TB status among HIV infected patients receiving QGIT...

Read More

A smoking cessation trial in HIV/AIDS...

A tobacco prevalence survey and smoking cessation trial among HIV infected patients in South Africa.

Read More

Understanding the impact of combined TB and...

We are developing models to understand the overlap of TB and HIV in three epidemiologically distinct settings (Canada, India,...

Read More