Scale-up and implementation of TB diagnostics including Xpert in Uganda

Location

Uganda, Uganda

Dates

05/25/2015 - 05/01/2016

PI

David Dowdy, MD, PhD, ScM

We are evaluating the implementation, cost-effectiveness, and potential epidemiological impact of scaling up Xpert across 19 stand-alone clinics and 2 larger referral networks across Uganda (including in Kampala).  We are also evaluating the role and cost-effectiveness of "triage" testing in peripheral clinics using CRP and other novel biomarkers.

Projects

Modeling the impact of novel TB drug regimens...

We are constructing mathematical models of TB epidemics in Southeast Asia, India, and Vietnam to explore the potential...

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Options for Patient-Centered Delivery of...

This individually randomized trial is evaluating the relative effectiveness of self-administered therapy, directly observed...

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Understanding the role of repeat testing and...

We have developed a Markov model of serial IGRA testing to help improve testing algorithms with TST vs. IGRA in low-risk...

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