Scale-up and implementation of TB diagnostics including Xpert in Uganda

Location

Uganda, Uganda

Dates

05/25/2015 - 05/01/2016

PI

David Dowdy, MD, PhD, ScM

We are evaluating the implementation, cost-effectiveness, and potential epidemiological impact of scaling up Xpert across 19 stand-alone clinics and 2 larger referral networks across Uganda (including in Kampala).  We are also evaluating the role and cost-effectiveness of "triage" testing in peripheral clinics using CRP and other novel biomarkers.

Projects

A smoking cessation trial in HIV/AIDS...

A tobacco prevalence survey and smoking cessation trial among HIV infected patients in South Africa.

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MDR TB treatment as prevention: modeling the...

We are using transmission modeling to evaluate the potential impact of expanding DST and access to MDR TB treatment in Vietnam,...

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A randomized trial of preventive therapy for...

We are evaluating the efficacy and cost-effectiveness of levofloxacin preventive therapy for adult contacts of MDR TB patients...

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Statins as adjunctive host-directed therapy...

This study will investigate the role of statins in combination with the first-line regimen for TB in the mouse model. In...

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mHealth for improved TB contact investigation...

This multicenter randomized study is evaluating the implementation, effectiveness, cost-effectiveness, and population-level...

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