Scale-up and implementation of TB diagnostics including Xpert in Uganda

Location

Uganda, Uganda

Dates

05/25/2015 - 05/01/2016

PI

David Dowdy, MD, PhD, ScM

We are evaluating the implementation, cost-effectiveness, and potential epidemiological impact of scaling up Xpert across 19 stand-alone clinics and 2 larger referral networks across Uganda (including in Kampala).  We are also evaluating the role and cost-effectiveness of "triage" testing in peripheral clinics using CRP and other novel biomarkers.

Projects

Impact of diabetes on TB treatment outcomes...

This is a study to prospectively enroll and follow TB patients co-infected with diabetes and TB patients without diabetes...

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Evaluating an automated system for...

We are evaluating the accuracy and cost-effectiveness of TBDx, an automated digital microscopy system, as a screening test to...

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The role of cell wall lipids in pathogenesis...

This study will use a combination of transcriptional, lipidomic, genetic, and imaging techniques to investigate whether...

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Comparative implementation and...

We are conducting a randomized comparative implementation trial across 56 sites in rural South Africa to evaluate three...

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