The role of cell wall lipids in pathogenesis of rifampin-resistant TB


Baltimore, Maryland, US


08/19/2013 - 07/31/2016


Petros Karakousis, MD

This study will use a combination of transcriptional, lipidomic, genetic, and imaging techniques to investigate whether phthiocerol dimycocerosate (PDIM) accumulation compensates for the fitness cost associated with M. tuberculosis rpoB mutation during host infection.


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