Understanding the impact of combined TB and HIV diagnosis in diverse epidemics

Location

Canada, Canada

Dates

10/01/2012 - 03/01/2016

PI

David Dowdy, MD, PhD, ScM

We are developing models to understand the overlap of TB and HIV in three epidemiologically distinct settings (Canada, India, and Uganda), including the potential role of different combined diagnostic strategies, given the different breakdown of populations at high TB risk, high HIV risk, and high combined TB/HIV risk.

Projects

Modeling the impact of spatially targeted TB...

We have developed transmission models to understand the impact of TB vaccination strategies that target hotspots of...

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Assessing the social value of novel regimens...

We are collaborating with investigators from the Berman Bioethics Institute to develop novel techniques for economic evaluation...

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Quantiferon gold test for detecting TB...

This is a cluster randomized trial comparing the time to known latent TB status among HIV infected patients receiving QGIT...

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Scale-up and implementation of TB diagnostics...

We are evaluating the implementation, cost-effectiveness, and potential epidemiological impact of scaling up Xpert across 19...

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