Nicole C. Ammerman, PhD, ScM

Staff

Titles:

Research Associate, Medicine, Infectious Disease, TB Center

Email:

nicole.ammerman@jhu.edu

Phone:

410-292-2957

SciVal:

SciVal Link

The fundamental basis of my work is to use science to advance the global control of tuberculosis and limit the suffering of people with tuberculosis and nontuberculous mycobacterial diseases. Specifically, my research efforts are focused on improving the treatment of these diseases by using in vitro and in vivo experimental chemotherapy models to evaluate the antimycobacterial activity of compounds, drugs, and regimens; and to study drug, host, and pathogen factors that influence treatment outcome. My research is translational; the ultimate goal of all my work is to provide reliable preclinical data that can be used to inform drug and regimen development and clinical trial design. Current research projects include investigation of the treatment-shortening potential of clofazimine in regimens for drug-susceptible tuberculosis; evaluation of a long-acting injectable formulation of bedaquiline for tuberculosis preventive therapy; and development of nontuberculous mycobacteria infection models for treatment studies.

Categories

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Projects

A Comprehensive Snapshot of Tuberculosis...

This study aims to find all cases of TB within an urban Ugandan community of 50,000 people and to characterize both the...

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Modeling to improve TB decision-making in the...

We are part of a large consortium that is constructing epidemic and economic models of TB and HIV in collaboration with the U.S....

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Impact of diabetes on TB treatment outcomes...

This is a study to prospectively enroll and follow TB patients co-infected with diabetes and TB patients without diabetes...

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Population-level impact of isoniazid...

We are collaborating with a team that conducted a randomized trial of IPT in Khayelitsha, South Africa, to extend their findings...

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MDR TB treatment as prevention: modeling the...

We are using transmission modeling to evaluate the potential impact of expanding DST and access to MDR TB treatment in Vietnam,...

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