Publications
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Reducing relapse in tuberculosis treatment: is it time to...
Published: 06/01/2015
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Costs and Consequences of Using Interferon-γ Release Assays for...
Published: 04/28/2015
There is growing concern that interferon-γ release assays (IGRAs) are being used off-label for the diagnosis of active tuberculosis (TB) disease in many high-burden settings, including India, where the background prevalence...
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The epidemiological advantage of preferential targeting of...
Published: 04/01/2015
Tuberculosis (TB) remains disproportionately concentrated among the poor, yet known determinants of TB reactivation may fail to explain observed disparities in disease rates according to wealth. Reviewing data on TB disparities in...
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Performance of a Novel Algorithm Using Automated Digital...
Published: 03/31/2015
TBDx automated microscopy is a novel technology that processes digital microscope images to identify acid-fast bacilli (AFB). TBDx as part of a diagnostic algorithm could improve the diagnosis of tuberculosis (TB), but its...
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Treatment for preventing tuberculosis in children and...
Published: 03/01/2015
IMPORTANCE:
Three months of a once-weekly combination of rifapentine and isoniazid for treatment of latent tuberculosis infection is safe and effective for persons 12 years or older. Published data for children are...
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C-reactive protein (CRP), interferon gamma-inducible protein 10...
Published: 02/26/2015
Objective: The association between pre-antiretroviral (ART) inflammation and immune activation and risk for incident tuberculosis (TB) after ART initiation among adults is uncertain. Design: Nested case-control study...
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Nuclear imaging: a powerful novel approach for tuberculosis.
Published: 02/19/2015
Nearly 20 years after the World Health Organization declared tuberculosis (TB) a global public health emergency, TB still remains a major global threat with 8.6 million new cases and 1.3 million deaths annually....
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Tuberculosis and Hepatic Steatosis Are Prevalent Liver Pathology...
Published: 02/19/2015
Liver disease epidemiology in sub-Saharan Africa has shifted as a result of HIV and the increased use of antiretroviral therapy leading to a need for updated data on common causes of liver disease. We retrospectively reviewed...
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Daily rifapentine for treatment of pulmonary tuberculosis: a...
Published: 02/19/2015
RATIONALE:
Rifapentine has potent activity in mouse models of tuberculosis chemotherapy but its optimal dose and exposure in humans are unknown.
OBJECTIVES:
We conducted a randomized, partially blinded...
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