Congratulations to Dr. Styliani Karanika, who is a JHU TRAC ESI, Mentee, and Developmental Awardee on this publication in the Journal of Clinical Investigation! The open-access full article is available here and the full citation is listed below.
Karanika S, Wang T, Yilma A, Ruelas Castillo J, Gordy JT, Bailey H, Quijada D, Fessler K, Tasneen R, Rouse Salcido EM, Shamma F, Harris HT, Chen F, Bates RE, Ton H, Meza J, Li Y, Taylor AD, Zheng JJ, Zhang J, Karantanos T, Maxwell AR, Nuermberger EL, Peske JD, Markham RB, Karakousis PC. Immunotherapy targeting drug-tolerant Mycobacterium tuberculosis persisters accelerates tuberculosis cure in preclinical models. J Clin Invest. 2026 Feb 3:e196648. doi: 10.1172/JCI196648. Epub ahead of print. PMID: 41632540.
Rohilla A, Singh AK, Koleske B, Srikrishna G, Bishai WR. Structure-based virtual screening and in vitro validation of inhibitors of cyclic dinucleotide phosphodiesterases ENPP1 and CdnP. Microbiol Spectr. 2024;12(1):e0201223. doi:10.1128/spectrum.02012-23
Tucker EW, Ruiz-Bedoya CA, Mota F, Erice C, Kim J, de Jesus P, Jahdav R, Bahr M, Flavahan K, Chen X, Peloquin CA, Freundlich JS, Jain SK. Linezolid does not improve bactericidal activity of rifampin-containing first-line regimens in animal models of TB meningitis. Int J Antimicrob Agents. 2024 Jan;63(1):107048. doi: 10.1016/j.ijantimicag.2023.107048. Epub 2023 Dec 5. PMID: 38061419; PMCID: PMC10841818.
Parveen, S., Shen, J., Lun, S. et al. Glutamine metabolism inhibition has dual immunomodulatory and antibacterial activities against Mycobacterium tuberculosis. Nat Commun 14, 7427 (2023). https://doi.org/10.1038/s41467-023-43304-0
Koleske BN, Jacobs WR Jr, Bishai WR. The Mycobacterium tuberculosis genome at 25 years: lessons and lingering questions. J Clin Invest. 2023;133(19):e173156. Published 2023 Oct 2. doi:10.1172/JCI173156
Yilma A, Bailey H, Karakousis PC, Karanika S. HIV/Tuberculosis Coinfection in Pregnancy and the Postpartum Period. J Clin Med. 2023;12(19):6302. Published 2023 Sep 29. doi:10.3390/jcm12196302
Dabitao D, Bishai WR. Sex and Gender Differences in Tuberculosis Pathogenesis and Treatment Outcomes. Curr Top Microbiol Immunol. 2023;441:139-183. doi: 10.1007/978-3-031-35139-6_6. PMID: 37695428.
Matern WM, Harris HT, Danchik C, et al. Functional Whole Genome Screen of Nutrient-Starved Mycobacterium tuberculosis Identifies Genes Involved in Rifampin Tolerance. Microorganisms. 2023;11(9):2269. Published 2023 Sep 9. doi:10.3390/microorganisms11092269
Jalbert E, Liu C, Mave V, Lang N, Kagal A, Valvi C, Paradkar M, Gupte N, Lokhande R, Bharadwaj R, Kulkarni V, Gupta A, Weinberg A.
Peters JS, McIvor A, Papadopoulos AO, Masangana T, Gordhan BG, Waja Z, Otwombe K, Letutu M, Kamariza M, Sterling TR, Bertozzi CR, Martinson NA, Kana BD. Differentially culturable tubercle bacteria as a measure of tuberculosis treatment response. Front Cell Infect Microbiol. 2023 Jan 12;12:1064148. doi: 10.3389/fcimb.2022.1064148. PMID: 36710965; PMCID: PMC9877613.
