Dr. Maunank Shah and Dr. Yuka Manabe named 2024 CDC TB Elimination Champions!
Congratulations to Dr. Shah and Dr. Manabe on being recognized as TB Elimination Champions!
Maunank Shah
Dr. Maunank Shah is the medical director for the Baltimore City Health Department TB Program. He is also president of the National Society of TB Clinicians. He chaired the development of the first national guidelines for TB respiratory isolation in community settings. Dr. Shah helped develop IDCrowd, a TB electronic consultation platform. He also co-invented video directly observed therapy software.
Learn about the other 2024 TB Elimination Champions on the CDC announcements
NIH clinical trial of tuberculous meningitis drug regimen begins
A trial of a new drug regimen to treat tuberculous meningitis (TBM) has started enrolling adults and adolescents in several countries where tuberculosis (TB) is prevalent. The Improved Management with Antimicrobial Agents Isoniazid Rifampicin Linezolid for TBM (IMAGINE-TBM) trial will compare a six-month regimen of four drugs with the nine-month, standard-of-care regimen for TBM. The study aims to generate evidence that could improve treatment for people with TBM. IMAGINE-TBM is sponsored by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, and implemented through the NIAID-funded Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections (ACTG).
IMAGINE-TBM is being led by JHU Center for TB Research faculty member, Dr. Vidya Mave along with our research partners in India.
The Johns Hopkins TRAC mourns the sudden death of our colleague and friend, Michelle Rudek, PharmD, PhD. Dr. Rudek served as Co-Director of our Pharmacology and Pharmacometrics Core and was a mentor to and collaborator of many. Dr. Rudek was Professor of Oncology and Medicine and Director of the Analytical Pharmacology Resource in the Sidney Kimmel Comprehensive Cancer Center in addition to her leadership role in the TRAC. Her loss will be deeply felt by the students, trainees, and investigators for whom she was a source of wisdom, guidance, and cheerful collaboration. We extend our profound condolences to her husband Paul Renaut and daughter Kiran.
Information on Dr. Rudek’s memorial service can be found below.
Study Shows FDA-Approved TB Regimen May Not Work Against the Deadliest Form of TB Due to Multidrug-Resistant Strains
Findings from a Johns Hopkins Children’s Center study in animal models show that a U.S. Food and Drug Administration (FDA)-approved antibiotic regimen for multidrug-resistant (MDR) tuberculosis (TB) may not work for TB meningitis. Studies in a small number of people also provide evidence that a new combination of drugs is needed to develop effective treatments for TB meningitis due to MDR strains.
Honoring Two Incredible Scientists and Allies of TAG
October 27, 2022
Every year our Research in Action Awards brings together those who’ve supported TAG’s work over our three decades, to honor a group of researchers, activists, and leaders who are fighting with us to end HIV, HCV, and TB. Two of those honorees this year are longtime TAG allies Dr. Amita Gupta and Dr. Kelly Elise Dooley, both infectious disease specialists who have made significant contributions to TB and HIV research globally.Read Article
Johns Hopkins Medicine-Led Consortium to Receive Up to $200 Million to Fight TB Globally