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News stories
San Antonio Report highlighted October IN-TRAC Patient Conference
A San Antonio Report highlighted the October IN-TRAC Patient Conference. The article, by Josh Archote, features the powerful stories of Jorge Sosa Martiarena, Sophia Martinez, and Lorenzo Salinas, offering an important look into the lived experience of TB and the impact it has on patients and families.
You can read the full article here: “‘I’m happy to be alive’: San Antonio residents share brutal experiences after tuberculosis diagnosis”
Welcome Dr. Bruno de Bezerril Andrade to JHU!
The JHU TRAC is delighted to formally welcome Dr. Bruno de Bezerril Andrade to JHU as a Professor of Medicine in the Division of Infectious Diseases and in the Department of International Health at BSPH!
A physician scientist who is internationally renowned for his contributions to immunology, infectious diseases, translational research and global health, Dr. Andrade joins Johns Hopkins from his current positions as Senior Investigator and Chief of the Laboratory of Clinical and Translational Research at the Oswaldo Cruz Foundation in Salvador, Brazil, one of the world’s leading biomedical research institutions, as Dean of Research and International Affairs at Clariens Educação, and as Scientific Director of MONSTER Research Institute, which is dedicated to nurturing young scientists from low- and middle-income countries and advocating for vulnerable populations including indigenous, homeless, and incarcerated communities.
Dr. Andrade brings to the division extensive expertise in global health, data science, artificial intelligence, and precision medicine. He will work closely with Department of Medicine’s data science/AI efforts to incorporate cutting-edge machine learning and AI applications in medicine and will enhance the division’s portfolio of clinical and translational research through developing and employing predictive analytics to improve patient outcomes related to tuberculosis, HIV, antimicrobial resistance, and emerging infections. He is also eager to enhance connections across Medicine, Public Health, and Engineering for multi-departmental efforts that leverage data science initiatives and AI advancement across Johns Hopkins in support of the School of Medicine’s clinical and translational research goals.
Dr. Andrade’s extensive networks in Brazil, throughout Latin America, and globally are an excellent complement to JHU’s existing bi- and multi-lateral research initiatives and offer opportunities for global collaboration and exchange programs for faculty and students alike.
He will be starting here on October 20, 2025.
“Landscape analysis of maternal tuberculosis surveillance and associated funding issues” WHO report published. Interviewees include Drs. Amita Gupta and Nicole Salazar-Austin
Union members drive prioritisation of pregnant women
2024 TRAC Developmental Awardees Announced
We are delighted to announce our 2024 TRAC Developmental Awardees!
Theodoros Karantanos, MD, PhD
Assistant Professor, Oncology, SOM
Project Title: Investigating the role of CCRL2 as an adjunctive host-directed therapeutic target in TB
Parastu Kasaie, PhD
Associate Scientist, Epidemiology, BSPH
Project Title: Characterizing the impact and strategies to optimize the effectiveness of multidrug-resistant tuberculosis preventive therapy among household contacts: a case study from Vietnam
Elizabeth Tucker, MD
Assistant Professor, Anesthesiology and Critical Care Medicine, SOM
Project Title: Brain-derived Extracellular Vesicles’ Participation in Tuberculous Meningitis Pathogenesis
Evan Shirey, MD
Postdoctoral Fellow, Pediatrics, SOM
Project Title: Evaluation of Risk Factors for Tuberculosis Infection Among Household Child and Adolescent Contacts in South Africa
Congratulations Dr Petros Karakousis, Dr Olivia Kates, Dr. Maunank Shah, and Dr. Cindy Sears and colleagues for their immense contributions to the joint publication of a new article series on TB isolation
Clinical Infectious Diseases and The Journal of Infectious Diseases have partnered to jointly publish a new article series on TB isolation. This collection was developed in response to new guidelines from the National Tuberculosis Coalition of America on the isolation of TB patients in community settings. Articles include clinical guidelines for the use of isolation in TB management, reviews of the history of isolation as a public health intervention and of the determinants of TB infectiousness, and a commentary on an ethics-informed public health guideline framework.
2023 TRAC Developmental Awardees Announced
We are delighted to announce our 2023 TRAC Developmental Awardees!
Anne Hamacher-Brady, PhD
Associate Scientist, Molecular Microbiology and Immunology, BSPH
Project Title: Deciphering Mitochondrial Responses to Mycobacterium tuberculosis Infection of Macrophages
Tess Ryckman, PhD
Instructor, Infectious Diseases, SOM
Project Title: Mycobacterium Tuberculosis Transmission Networks in Urban Uganda: Evidence from Spatial and Genomic Data
Manish Gupta, PhD
Postdoctoral Research Fellow, Infectious Diseases, SOM
Project Title: Deciphering the hormonal and genetic mechanisms mediating sex differences in tuberculosis: using a sst1-susceptible ‘Four Core Genotype’ mouse model
Sadiya Parveen, PhD
Postdoctoral Research Fellow, Infectious Diseases, SOM
Project Title: Characterization of immunometabolic drivers of tuberculosis infection
NIH clinical trial of tuberculous meningitis drug regimen begins
A trial of a new drug regimen to treat tuberculous meningitis (TBM) has started enrolling adults and adolescents in several countries where tuberculosis (TB) is prevalent. The Improved Management with Antimicrobial Agents Isoniazid Rifampicin Linezolid for TBM (IMAGINE-TBM) trial will compare a six-month regimen of four drugs with the nine-month, standard-of-care regimen for TBM. The study aims to generate evidence that could improve treatment for people with TBM. IMAGINE-TBM is sponsored by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, and implemented through the NIAID-funded Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections (ACTG).
IMAGINE-TBM is being led by JHU Center for TB Research faculty member, Dr. Vidya Mave along with our research partners in India.
In Memoriam
Michelle Rudek, PharmD, PhD
The Johns Hopkins TRAC mourns the sudden death of our colleague and friend, Michelle Rudek, PharmD, PhD. Dr. Rudek served as Co-Director of our Pharmacology and Pharmacometrics Core and was a mentor to and collaborator of many. Dr. Rudek was Professor of Oncology and Medicine and Director of the Analytical Pharmacology Resource in the Sidney Kimmel Comprehensive Cancer Center in addition to her leadership role in the TRAC. Her loss will be deeply felt by the students, trainees, and investigators for whom she was a source of wisdom, guidance, and cheerful collaboration. We extend our profound condolences to her husband Paul Renaut and daughter Kiran.
Information on Dr. Rudek’s memorial service can be found below.
https://www.dignitymemorial.com/obituaries/columbia-md/michelle-renaut-11532280