Study Shows FDA-Approved TB Regimen May Not Work Against the Deadliest Form of TB Due to Multidrug-Resistant Strains

Findings from a Johns Hopkins Children’s Center study in animal models show that a U.S. Food and Drug Administration (FDA)-approved antibiotic regimen for multidrug-resistant (MDR) tuberculosis (TB) may not work for TB meningitis. Studies in a small number of people also provide evidence that a new combination of drugs is needed to develop effective treatments for TB meningitis due to MDR strains.

2022 TRAC Developmental Awardees Announced

We are delighted to announce our inaugural round of TRAC Developmental Awardees! 

Subhra Chakraborty, PhD, MPH
Associate Scientist, International Health, BSPH
Project Title: Development of a novel diagnostic assay for pediatric tuberculosis

Styliani Karanika, MD 
Assistant Professor of Medicine, SOM
Project Title: A therapeutic mRNA vaccine targeting Mycobacterium tuberculosis persisters

Eileen Scully, MD, PhD 
Associate Professor of Medicine, SOM
Project Title: Exploring host determinants of Mycobacterium tuberculosis control 

Sourya Shrestha, PhD
Assistant Scientist, Epidemiology, BSPH
Project Title: Assessing the role of preventive therapy in advancing goals of TB Free Nepal 

Jeffrey Tornheim, MD, MPH 
Assistant Professor of Medicine and Pediatrics, SOM
Project Title: Determination of the mid-treatment molecular clock for multidrug resistant tuberculosis 



Honoring Two Incredible Scientists and Allies of TAG

October 27, 2022 

Every year our Research in Action Awards brings together those who’ve supported TAG’s work over our three decades, to honor a group of researchers, activists, and leaders who are fighting with us to end HIV, HCV, and TB. Two of those honorees this year are longtime TAG allies Dr. Amita Gupta and Dr. Kelly Elise Dooley, both infectious disease specialists who have made significant contributions to TB and HIV research globally. Read Article


Johns Hopkins Medicine-Led Consortium to Receive Up to $200 Million to Fight TB Globally