Mission

The Mission of the Johns Hopkins Center for Tuberculosis Research (CTR) is to contribute to global tuberculosis control through a range of research and training initiatives in epidemiology, diagnostics, drug development, clinical trials, pathogenesis and basic biology. The CTR, founded in 1998, is comprised of a multi-disciplinary team of scientists working to combat Mycobacterium tuberculosis, a pathogen that causes 1.5 to 2 million deaths every year. Our faculty is drawn from the Schools of Medicine, Bloomberg School of Public Health and Nursing, with a research portfolio that is broad and interdisciplinary. Our major strengths are molecular biology, epidemiology, clinical trials, drug development and mathematical modeling; additional areas of emphasis include animal models, pathogenesis, vaccine development, behavioral research, immunology, and diagnostics.

While research is a primary focus, developing the next cadre of scientists who will contribute to future control efforts is also a major goal. Students from medicine, public health, and nursing have found that the range of topics and locations offer excellent training opportunities. With the slogan, “From bench to bedside and beyond,” the CTR covers everything from genetic epidemiology of TB to population-level studies that have played a major role in forming global policies for TB control.

Events

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Projects

Modeling the impact of spatially targeted TB...

We have developed transmission models to understand the impact of TB vaccination strategies that target hotspots of...

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Understanding the impact of combined TB and...

We are developing models to understand the overlap of TB and HIV in three epidemiologically distinct settings (Canada, India,...

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A randomized trial of preventive therapy for...

We are evaluating the efficacy and cost-effectiveness of levofloxacin preventive therapy for adult contacts of MDR TB patients...

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Population-level impact of isoniazid...

We are collaborating with a team that conducted a randomized trial of IPT in Khayelitsha, South Africa, to extend their findings...

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Quantitative assessment of the tipping point...

Quantitative methods will be used to study Mtb dynamics to determine the tipping point for macrophage infection, which depends...

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