The weekly Tuberculosis Research Advancement Center (TRAC) Seminar Series is held on Wednesdays from 12:00 – 1:00 PM ET in CRB-2, 1M.13 or via Zoom. Add to Calendar
RSVP for lunch by Tuesday, 10/8 by 12pm.
“Personalized dosing of TB treatment”
Scott Heysell MD, MPH
Thomas H. Hunter Assoc. Professor of International Medicine
Division of Infectious Diseases and International Health
Director, Center for Global Health Equity
University of Virginia
Dr. Heysell’s research group focuses on pharmacokinetics and pharmacodynamics to improve treatment outcomes in patients with mycobacterial diseases or with comorbid HIV, diabetes, and/or malnutrition. Consequent secondary areas of interest include the development of laboratory assays for pharmacodynamics studies, the building of infrastructure and expertise for community-based research in tuberculosis-endemic settings, and clinical trials of tuberculosis drug regimens.
The October TRAC Seminar Series is presented by the Pharmacology & Pharmacometrics Core.
Join via Zoom – **New link for 2024-2025**
Https://jhjhm.zoom.us/j/92431052728?pwd=STVlQXREQm1ITlZBZWNxWE05UzdFQT09
Meeting ID: 924 3105 2728
Passcode: 175279
This week, in lieu of a TRAC-specific seminar, we will be meeting in CRB-2, 1M.13 from 10:45am – 12:30pm to livestream Session 4 (Approaches and tools in TB drug development and optimization and in treatment of patients) from the International Workshop on Clinical Pharmacology of Tuberculosis Drugs 2024. TRAC Pharmacology and Pharmacometrics Core Director Eric Nuermberger, MD is a member of the workshop organizing committee. Register to join for lunch here.
For those interested in joining virtually, registration for the two day workshop is free so please register directly with them to receive Zoom information. The full 2-day agenda is available on the meeting website and we encourage you to join for any other sessions that might be of interest. Add to Calendar.
International Workshop on Clinical Pharmacology of Tuberculosis Drugs 2024
JHU TRAC Lunch & Livestream from 10:45am – 12:30pm in CRB-2, 1M.13. Register here for the lunch order to be delivered at 11:15am.
| Session 4 Approaches and tools in TB drug development and optimization and in treatment of patients |
| Chairs: Gerry Davies & Charles Peloquin |
|
10:45 AM ET |
Advancing tuberculosis therapy with co-crystals: a comprehensive review |
Shagun Gogna |
|
11:00 AM ET |
Using machine learning to expedite area under the curve calculation for PK/PD analysis |
Abdullah Alsultan |
|
11:15 AM ET |
Machine-learning time-to-event analysis for prediction of 2-month culture conversion with phase 2a information in tuberculosis drug development |
Huifang You |
|
11:30 AM ET |
On our way to personalized therapy: using therapeutic drug monitoring of moxifloxacin for an external pharmacokinetic model evaluation |
Emily Behrens |
|
11:45 AM ET |
Evaluation of QT prolongation during bedaquiline treatment using a time-varying tuberculosis-specific correction factor (QTcTBT) |
Thanakorn Vongjarudech |
|
12:00 PM ET |
Rapporteur session |
Ulrika Simonsson |
The October TRAC Seminar Series is presented by the Pharmacology & Pharmacometrics Core.
The weekly Tuberculosis Research Advancement Center (TRAC) Seminar Series is held on Wednesdays from 12:00 – 1:00 PM ET in CRB-2, 1M.13 or via Zoom. Add to Calendar.
“Advanced Molecular Imaging for Infectious Diseases“
Sanjay K. Jain, MD
Professor of Pediatrics, Radiology and Radiological Sciences and International Health
Director, Center for Infection and Inflammation Imaging Research
Co-Director, JHU TRAC MIAMI Core
Sanjay K Jain, M.D. is Professor of Pediatrics, Radiology & Radiological Sciences and International Health at the Johns Hopkins University. He directs the Center for Infection and Inflammation Imaging Research and is a member of the Center for TB Research at Johns Hopkins. Dr. Jain is also the Vice Chair for Basic & Translational Research in the Department of Pediatrics. His primary research interests include the development of novel molecular imaging technologies for infectious diseases, bacterial pathogenesis, pediatric tuberculosis (TB), and TB meningitis. Alongside his wife, he is raising three children.
The September TRAC Seminar Series is presented by the Microbiology, Immunology, Animal Modeling & Imaging (MIAMI) Core.
Join via Zoom – **New link for 2024-2025**
Https://jhjhm.zoom.us/j/92431052728?pwd=STVlQXREQm1ITlZBZWNxWE05UzdFQT09
Meeting ID: 924 3105 2728
Passcode: 175279
RSVP for lunch by Tuesday, 9/24 by 12pm.
The weekly Tuberculosis Research Advancement Center (TRAC) Seminar Series is held on Wednesdays from 12:00 – 1:00 PM ET in CRB-2, 1M.13 or via Zoom. Add to calendar.
“Type VII secretion systems in M.tb virulence”
Benjamin Koleske, BS
MD/PhD Candidate, Department of Biochemistry, Cellular and Molecular Biology
Johns Hopkins University School of Medicine
Benjamin Koleske is an MD/PhD candidate in the lab of Dr. William Bishai at the Johns Hopkins University School of Medicine. His work focuses on secretory proteins of Mycobacterium tuberculosis and their role in virulence. He previously trained at Yale University in the lab of Dr. Daniel DiMaio, where he studied viral oncogenes that activate host growth factor receptors.
The September TRAC Seminar Series is presented by the Microbiology, Immunology, Animal Modeling & Imaging (MIAMI) Core.
Join via Zoom – **New link for 2024-2025**
Https://jhjhm.zoom.us/j/92431052728?pwd=STVlQXREQm1ITlZBZWNxWE05UzdFQT09
Meeting ID: 924 3105 2728
Passcode: 175279
RSVP for lunch by Tuesday, 9/10 by 12pm.
The Tuberculosis Research Advancement Center (TRAC) Visiting Faculty Seminar will be held on Wednesday, September 4th from 12:00 – 1:00 PM ET in CRB-2, 1M.13 or via Zoom. RSVP for lunch by Tuesday, 9/3 by 12pm. Add to Calendar.
” Targeting M. tuberculosis persisters through the inhibition of the trehalose catalytic shift”
Hyungjin Eoh, DVM, PhD
Associate Professor of Molecular Microbiology and Immunology (MMI),
Keck School of Medicine (KSoM),
University of Southern California (USC)
Dr. Eoh is an accomplished Associate Professor of Dept. Molecular Microbiology and Immunology at USC KSOM. Dr. Eoh’s research focuses on discovery of novel tuberculosis antibiotics by thoroughly understanding the metabolic strategies underlying Mycobacterium tuberculosis development of drug tolerance and resistance. Dr. Eoh has published over 50 peer-reviewed articles in top-tier scientific journals and has received numerous grants from prestigious agencies such as NIH, Donald E. & Delia B. Baxter Foundation and American Lung Association to support his research. In addition, Dr. Eoh is a sought-after speaker at international conferences and has received awards for the contributions to his research field.
This Visiting Faculty Seminar is presented by the Microbiology, Immunology, Animal Modeling & Imaging (MIAMI) Core.
Join via Zoom: New link for 2024-2025
Topic: TRAC Seminar Series
Time: Every week on Wednesday at 12:00 PM Eastern Time (US and Canada)
Join Zoom Meeting: Https://jhjhm.zoom.us/j/92431052728?pwd=STVlQXREQm1ITlZBZWNxWE05UzdFQT09
Meeting ID: 924 3105 2728
Passcode: 175279
RSVP for lunch by Tuesday, 9/3 by 12pm.
The Tuberculosis Research Advancement Center (TRAC) and The Center for Global Non-Communicable Disease Research present a visiting faculty lunch seminar with Dr. Richard Oberhelman on Friday, July 12th from 1:00 – 2:00 PM ET in the Tumulty Conference Room, Room 9019, 1830 E. Monument Street.
” Can We Increase the Diagnostic Accuracy for Tuberculosis in Children with Blood Biomarkers and Lung Ultrasound? The Bolivia Pediatric TB Study”
RSVP for lunch here.
The weekly Tuberculosis Research Advancement Center (TRAC) Seminar Series is held on Thursdays from 12:00 – 1:00 PM ET in CRB-2, 1M.13 and Zoom. RSVP to join us for lunch by 12pm on Wednesday, May 29th. Add to Calendar
“Journal Club: Pregnancy Outcomes in Women Screened for Tuberculosis Infection in Swedish Antenatal Care” Read the article here.
Natalia Hernandez Morfin, MD, MPH
Senior Research Assistant, Division of Infectious Diseases
Johns Hopkins University School of Medicine
Natalia Hernandez Morfin, MD, MPH, is a senior research Assistant in the Infectious Diseases Department at Johns Hopkins University, School of Medicine. She received her medical degree from the Universidad de Guadalajara in Mexico and completed her residency in Pediatrics at the National Institute of Pediatrics in Mexico. She continued her training at Johns Hopkins School of Public Health to earn a Master of Public Health (MPH) in Epidemiology and Biostatistics. Her research interests focus on maternal and child health, infectious diseases, and tuberculosis.
The May TRAC Seminar Series is organized by Dr. Nicole Salazar-Austin and Dr. Ahizechukwu C. Eke through the Clinical Core and will focus on TB & Pregnancy.
Join via Zoom – **New link w/ Passcode**
https://jhjhm.zoom.us/j/99512605810?pwd=NitKVjhqOFRCVURneE12Z2FzN21DQT09
Meeting ID: 995 1260 5810
Passcode: 107907
The weekly Tuberculosis Research Advancement Center (TRAC) Seminar Series is held on Thursdays from 12:00 – 1:00 PM ET in CRB-2, 1M.13 and Zoom. RSVP to join us for lunch by 12pm on Wednesday, May 15th. Add to Calendar.
“Scars of one disease in two bodies: Community statement for TB and pregnancy research”
Buci Beko is a drug-resistant TB survivor. Buci worked for Doctors without Borders on a Drug-Resistant TB program as a patient support supervisor and a counselor for families that are infected and affected with Drug-Resistant TB in Khayelitsha Cape Town (South Africa). Buci is a TB proof member and tireless TB advocate advocating to improve care for people impacted by Drug-Resistant TB. Buci has a degree as a social worker.
Oxana Rucsineanu has a Master in Public Health and a Licentiate in Education. Oxana is a DR-TB survivor herself and is leading a patient-led Civil Society Organisation in Moldova, which provides psychosocial support, peer education and activities to end stigma, focusing on the rights of people affected by TB, comprehensive approaches to TB care and engaging communities in research and development. She is committed to advocating for constructive partnerships and efficient treatment processes as well as to making TB voices heard in the national and global TB response. Oxana is an active member of the TB National NGOs and Key Affected Populations Platforms, Country Coordinating Mechanism and TB and HIV National Committee of Experts in the country. Regionally and internationally, Oxana is affiliated to TB Global Community Advisory Board, Global Coalition of TB Activists, TB People, South Eastern Europe Regional Community network (SEE-RCN) and World Health Organization Regional Committee of TB, HIV and Viral Hepatitis (RCC-THV). Furthermore, for several years Oxana is providing specific consultant services at regional level and has experience in collaboration with the WHO Europe, TB Europe Coalition, and Eurasian Harm Reduction Association etc.
The May TRAC Seminar Series is organized by Dr. Nicole Salazar-Austin and Dr. Ahizechukwu C. Eke through the Clinical Core and will focus on TB & Pregnancy.
Join via Zoom – **New link w/ Passcode**
https://jhjhm.zoom.us/j/99512605810?pwd=NitKVjhqOFRCVURneE12Z2FzN21DQT09
Meeting ID: 995 1260 5810
Passcode: 107907
The weekly Tuberculosis Research Advancement Center (TRAC) Seminar Series is held on Thursdays from 12:00 – 1:00 PM ET in CRB-2, 1M.13 and Zoom. RSVP to join us for lunch by 12pm on Wednesday, May 8th. Add to Calendar
“NASEM Report Findings and Implications for Research”
Ahizechukwu C. Eke, MD PhD MPH
Associate Professor
Division of Maternal Fetal Medicine, Department of Gynecology and Obstetrics
Johns Hopkins University School of Medicine
Ahizechukwu Eke, MD PhD MPH is an Associate Professor and Director of Maternal Fetal Medicine research within the Division of Maternal Fetal Medicine, Department of Gynecology and Obstetrics at the Johns Hopkins University School of Medicine. He received his medical degree from the University of Calabar School of Medicine in Nigeria, and completed 2 residencies in Obstetrics & Gynecology at the Nnamdi Azikiwe University College of Medicine, Nigeria and Michigan State University respectively. He continued his training at Harvard University to earn a Master of Public Health (MPH) in Health Policy & Management. Dr Eke completed a dual Fellowship in Maternal Fetal Medicine and Clinical Pharmacology at the Johns Hopkins University School of Medicine, and finished a PhD in Clinical Investigation at the Johns Hopkins University School of Public Health. He is quadruple-board certified (in Obstetrics & Gynecology (x2), Clinical Pharmacology, and Maternal Fetal Medicine).
His research interests include understanding the pharmacokinetics (PK), pharmacodynamics (PD), pharmacoepidemiology, pharmacogenomics, and pharmacomicrobiomics of drug use in pregnant women. He has been working with the International Maternal Pediatric Adolescent AIDS Clinical Trials Network (IMPAACT) as principal investigator and co-investigator for numerous pharmacokinetic drug studies in pregnant women. Dr Eke has served the American College of Obstetricians and Gynecologists (ACOG) in numerous leadership positions. He currently serves on the ACOG National Clinical Guidelines Committee, and on several other national and international OBGYN committees, including an Editorial Board member of Obstetrics & Gynecology (the Green Journal) and the National Academy of Sciences, Engineering and Medicine (NASEM’s) committee for addressing legal, ethical, regulatory, and policy issues for research specific to pregnant and lactating persons. Dr Eke has over severalPubMed cited peer-reviewed research publications, and has won several teaching and research awards.
The May TRAC Seminar Series is organized by Dr. Nicole Salazar-Austin and Dr. Ahizechukwu C. Eke through the Clinical Core and will focus on TB & Pregnancy.
Join via Zoom – **New link w/ Passcode**
https://jhjhm.zoom.us/j/99512605810?pwd=NitKVjhqOFRCVURneE12Z2FzN21DQT09
Meeting ID: 995 1260 5810
Passcode: 107907
The weekly Tuberculosis Research Advancement Center (TRAC) Seminar Series is held on Thursdays from 12:00 – 1:00 PM ET in CRB-2, 1M.13 and Zoom. RSVP to join us for lunch by 12pm on Wednesday, May 1st. Add to Calendar
“Tuberculosis and pregnancy: a focus on levofloxacin”
Jennifer Hughes, MBBCh
Desmond Tutu TB Centre (DTTC)
Department of Paediatrics and Child Health
Faculty of Medicine and Health Sciences
Stellenbosch University, Cape Town, South Africa
Dr. Jennifer Hughes graduated from the University of Cardiff, Wales (United Kingdom), in 2005 with a degree in medicine and surgery and a bachelor’s degree in Public Health. She worked as a junior doctor in a rural district hospital in South Africa before joining Médecins Sans Frontières (MSF, Doctors Without Borders), where she worked with local stakeholders to run the decentralised drug-resistant tuberculosis programme in Khayelitsha. She was involved in the early roll-out of bedaquiline and delamanid in South Africa and is still a member of the National Clinical Advisory Committee for management of DR-TB in the country.
Since 2017, Jennifer has been working as a research doctor at the Desmond Tutu TB Centre (DTTC), under the Department of Paediatrics and Child Health at Stellenbosch University in Cape Town. Her main research focus is the pharmacokinetics and safety of new drugs and optimised treatment regimens in children and pregnant women with drug-resistant TB.
The May TRAC Seminar Series is organized by Dr. Nicole Salazar-Austin and Dr. Ahizechukwu C. Eke through the Clinical Core and will focus on TB & Pregnancy.
Join via Zoom – **New link w/ Passcode**
https://jhjhm.zoom.us/j/99512605810?pwd=NitKVjhqOFRCVURneE12Z2FzN21DQT09
Meeting ID: 995 1260 5810
Passcode: 107907
